Nature Communications (May 2019)
Three phylogenetic groups have driven the recent population expansion of Cryptococcus neoformans
- P. M. Ashton,
- L. T. Thanh,
- P. H. Trieu,
- D. Van Anh,
- N. M. Trinh,
- J. Beardsley,
- F. Kibengo,
- W. Chierakul,
- D. A. B. Dance,
- S. Rattanavong,
- V. Davong,
- L. Q. Hung,
- N. V. V. Chau,
- N. L. N. Tung,
- A. K. Chan,
- G. E. Thwaites,
- D. G. Lalloo,
- C. Anscombe,
- L. T. H. Nhat,
- J. Perfect,
- G. Dougan,
- S. Baker,
- S. Harris,
- J. N. Day
Affiliations
- P. M. Ashton
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- L. T. Thanh
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- P. H. Trieu
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- D. Van Anh
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- N. M. Trinh
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- J. Beardsley
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- F. Kibengo
- MRC/UVRI and LSHTM Uganda Research Unit
- W. Chierakul
- Mahidol Oxford Tropical Medicine Research Unit
- D. A. B. Dance
- Nuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford
- S. Rattanavong
- Lao–Oxford–Mahosot Hospital–Wellcome Trust Research Unit
- V. Davong
- Lao–Oxford–Mahosot Hospital–Wellcome Trust Research Unit
- L. Q. Hung
- Cho Ray Hospital
- N. V. V. Chau
- Hospital for Tropical Diseases
- N. L. N. Tung
- Hospital for Tropical Diseases
- A. K. Chan
- Sunnybrook Health Sciences Centre, University of Toronto
- G. E. Thwaites
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- D. G. Lalloo
- Liverpool School of Tropical Medicine
- C. Anscombe
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- L. T. H. Nhat
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- J. Perfect
- Department of Medicine and Department of Molecular Genetics and Microbiology, Division of Infectious Diseases, Duke University
- G. Dougan
- Wellcome Trust-Cambridge Centre for Global Health Research
- S. Baker
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- S. Harris
- Pathogen Genomics, The Wellcome Trust Sanger Institute
- J. N. Day
- Wellcome Trust Asia Programme, Oxford University Clinical Research Unit
- DOI
- https://doi.org/10.1038/s41467-019-10092-5
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 10
Abstract
Cryptococcus neoformans is an opportunistic fungal pathogen which primarily affects people with immune defects including those living with HIV. Here, the authors sequence and analyze genomes of 699 isolates, and identify recent population expansion driven by three phylogenetic groups.
