Annals of Clinical and Translational Neurology (Mar 2020)

Optically pumped magnetoencephalography in epilepsy

  • Umesh Vivekananda,
  • Stephanie Mellor,
  • Tim M. Tierney,
  • Niall Holmes,
  • Elena Boto,
  • James Leggett,
  • Gillian Roberts,
  • Ryan M. Hill,
  • Vladimir Litvak,
  • Matthew J. Brookes,
  • Richard Bowtell,
  • Gareth R. Barnes,
  • Matthew C. Walker

DOI
https://doi.org/10.1002/acn3.50995
Journal volume & issue
Vol. 7, no. 3
pp. 397 – 401

Abstract

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Abstract We demonstrate the first use of Optically Pumped Magnetoencephalography (OP‐MEG) in an epilepsy patient with unrestricted head movement. Current clinical MEG uses a traditional SQUID system, where sensors are cryogenically cooled and housed in a helmet in which the patient’s head is fixed. Here, we use a different type of sensor (OPM), which operates at room temperature and can be placed directly on the patient’s scalp, permitting free head movement. We performed OP‐MEG recording in a patient with refractory focal epilepsy. OP‐MEG‐identified analogous interictal activity to scalp EEG, and source localized this activity to an appropriate brain region.