Factors influencing receptivity to future screening options for pancreatic cancer in those with and without pancreatic cancer family history

Abstract

Abstract Background Pancreatic cancer (PC) is considered the most lethal cancer and approximately 10% of PC is hereditary. The purpose of the study was to assess attitudes of at-risk family members with two or more relatives affected with pancreas cancer (PC) toward PC risk and future screening options. Methods At-risk family members and primary care controls were surveyed regarding perceived PC risk, PC worry/concern, attitude toward cancer screening, screening test accuracy, and intentions regarding PC screening via blood testing or more invasive endoscopic ultrasound (EUS). Results PC family members reported greater perceived risk of PC than controls (54% vs. 6%, respectively, p 89%) receptivity to the potential PC screening options presented, though receptivity was greater among PC family members as compared to controls (p Conclusions Receptivity to screening options for PC appears high. Clinicians should address behavioral and genetic risk factors for PC and foster appropriate concern regarding PC risk among at-risk individuals.

Keywords

• Pancreatic cancer
• Health behavior
• Perceived risk
• Screening intentions