Direct Intracellular Visualization of Ebola Virus-Receptor Interaction by <i>In Situ</i> Proximity Ligation

Abstract

Ebola virus causes episodic but increasingly frequent outbreaks of severe disease in Middle Africa, as shown by the recently overcome second largest outbreak on record in the Democratic Republic of Congo. Despite considerable effort, FDA-approved antifiloviral therapeutics or targeted interventions are not available yet.