Nature Communications (May 2019)

Altered respiratory virome and serum cytokine profile associated with recurrent respiratory tract infections in children

  • Yanpeng Li,
  • Xuemin Fu,
  • Jinmin Ma,
  • Jianhui Zhang,
  • Yihong Hu,
  • Wei Dong,
  • Zhenzhou Wan,
  • Qiongfang Li,
  • Yi-Qun Kuang,
  • Ke Lan,
  • Xia Jin,
  • Jian-Hua Wang,
  • Chiyu Zhang

DOI
https://doi.org/10.1038/s41467-019-10294-x
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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Here, the authors determine the respiratory virome and serum cytokine profile in children diagnosed with acute respiratory tract infections (ARTI) and show that relative abundance of Propionibacterium phages as well as serum levels of TIMP-1 and PDGF-BB are increased in multiple ARTIs compared with single ARTI.