Properties evaluation of mesoporous silica nanopowders doped with manganese dioxide produced by a pulsed electron beam evaporation for biomedical applications

Abstract

The researched manganese-doped mesoporous silica nanopowder (NP) SiO2 — MnO2 with different dopant concentrations has been carried out by a physical method of the electron beam evaporation in vacuum on NANOBIM-2 installation. Basic analyses of NP demonstrate high porosity and ferromagnetic properties. Cytotoxicity experiments on cells showed that NP exerted low toxicity. The loading experiments using a spectrophotometer demonstrate interaction of the Amoxicillin drug with the surface of NP.

Keywords

• mesoporous silica nanopowders doped with manganese dioxide
• active targeted drug delivery