TRIM24 controls induction of latent HIV-1 by stimulating transcriptional elongation

Affiliations

Riley M. Horvath: Department of Biochemistry and Molecular Biology, Molecular Epigenetics Group, LSI, University of British Columbia
Matthew Dahabieh: Department of Biochemistry and Molecular Biology, Molecular Epigenetics Group, LSI, University of British Columbia
Tom Malcolm: Department of Biochemistry and Molecular Biology, Molecular Epigenetics Group, LSI, University of British Columbia
Ivan Sadowski: Department of Biochemistry and Molecular Biology, Molecular Epigenetics Group, LSI, University of British Columbia

Abstract

TRIM24 regulates transcriptional elongation from the HIV-1 promoter through its interaction with TFII-I, and by recruitment of P-TEFb.