Chinese Journal of Contemporary Neurology and Neurosurgery (Jan 2022)
"Culprit antibody" concept based diagnosis and treatment strategy of autoimmune encephalitis
Abstract
Autoimmune encephalitis (AE) with autoantibodies targeting neuronal surface proteins, ion channels or synaptic surface receptors is a major component of neuroimmune diseases. The detection of autoantibodies is of great value for the diagnosis, treatment and prognosis. Culprit antibody solve the problem of the coexistence of different autoantibodies in the same patient. This article review the relationship between culprit antibody and clinical phenotype in AE.
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