Silibinin suppresses glioblastoma cell growth, invasion, stemness, and glutamine metabolism by YY1/SLC1A5 pathway

Liu Ming; Liu Xipeng; Qiao Jianxin; Cao Bing

doi:10.1515/tnsci-2022-0333

Translational Neuroscience (Feb 2024)

Silibinin suppresses glioblastoma cell growth, invasion, stemness, and glutamine metabolism by YY1/SLC1A5 pathway

Liu Ming,
Liu Xipeng,
Qiao Jianxin,
Cao Bing

Affiliations

Liu Ming: Department of Neurosurgery, The First Affiliated Hospital of Hebei North University, 12 Changqing Road, Qiaoxi District, Zhangjiakou City, 075000, Hebei Province, China
Liu Xipeng: Department of Neurosurgery, The First Affiliated Hospital of Hebei North University, 12 Changqing Road, Qiaoxi District, Zhangjiakou City, 075000, Hebei Province, China
Qiao Jianxin: Department of Neurosurgery, The First Affiliated Hospital of Hebei North University, 12 Changqing Road, Qiaoxi District, Zhangjiakou City, 075000, Hebei Province, China
Cao Bing: Department of Neurosurgery, The First Affiliated Hospital of Hebei North University, 12 Changqing Road, Qiaoxi District, Zhangjiakou City, 075000, Hebei Province, China

DOI: https://doi.org/10.1515/tnsci-2022-0333
Journal volume & issue: Vol. 15, no. 1
pp. 1231 – 51

Abstract

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Silibinin has been found to inhibit glioblastoma (GBM) progression. However, the underlying molecular mechanism by which Silibinin regulates GBM process remains unclear.

Published in Translational Neuroscience

ISSN: 2081-6936 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.degruyter.com/view/j/tnsci

About the journal

Abstract

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