Медицинский совет (Dec 2014)
Selection of the optimal method of pain therapy for typical surgery at ENT clinic based on the evaluation of the circadian rhythm of heart rate
Abstract
The article describes the characteristic features of circadian rhythms in heart rate under normal and stress conditions as a result of surgical interventions at ENT clinic using various analgesic schemes. The study included 45 physically healthy males aged 25 to 40 years divided into 4 groups depending on the method of perioperative analgesia: metamizole sodium group (n = 10), ketorolac group (n = 10), trimeperidine group (n = 10) and group of patients with anesthetic support (ketamine group, n = 5). A qualitative analysis of circadian profiles of heart rate was conducted. The study found that metamizole sodium and ketorolac groups were more likely to demonstrate changes in the configuration of the circadian HR profile, absence of sustained ventricular tachycardia and mild bradycardia at night. Trimeperidine group tended to tachycardia in the evening and night, though the heart rate profile did not show any marked deviations. In ketamine group, circadian HR rhythms were most positive. Recommendations are provided on the choice of the best method of analgesia in patients with concomitant diseases of the cardiovascular system.
Keywords
