Crystallographic, structural elucidation and electronic interactions of novel ampf crystals for biomedicinal use by theory and practice as an anti-diabetic agent

Abstract

Fumaric acid is the trans-isomer in the structural effectiveness of the titled salt of the Zwitter ionic nature of the entitled specimen as C6H9N2+.C4H3O4−, the fumarate anions are linked to adjacent anions and 2-amino-4 methyl pyridinium cations via N—H…O hydrogen bonds, forming a three-dimensional supramolecular structure of novel and newly developed 2 Amino 4 methyl pyridinium Fumarate (AMPF) single crystals. The crystal structure also shows a weak C—H…O hydrogen bond between adjacent anions. The crystal is of the monoclinic type of system with space group P21/n, molecular weight of the specimen is 224.22 and chemical formula of AMPF is C10H12N2O4. The crystal identified as novel one and is the persuasive candidate for electronic studies by atomic interactions specifically without surface property and for best medication tool for anti-diabetic as significant bio medicinal activity by pyridine and fumarate based on IC50 data for micro as well as nano scalings using alpha amylase and reported here the interaction patterns, simulated pattern, Platon plot also with structural portrayal with ambience and diffusivity.

Keywords

• Novel crystal
• Organic
• Monoclinic
• Electronic interactions
• Anti-diabetic