Incidental Langerhans cell histiocytosis associated with metastatic neuroendocrine tumor in the adult liver

Abstract

Abstract This is an unusual adult case of a metastatic well‐differentiated neuroendocrine tumor with incidentally discovered subtle involvement of Langerhans cell histiocytosis (LCH), a clonal proliferation of Langerhans cells. It is important to recognize that LCH can often co‐exist with other malignancies (solid > hematologic).

Keywords

• BRAF mutation
• langerhans cell histiocytosis (LCH)
• liver
• MAP2K1 mutation
• neuroendocrine tumor (NET)