Case Reports in Neurology (Feb 2024)

Disseminated aspergillosis with mediastinal invasion causing fatal stroke in an immunocompetent young man

  • Robert Yarham,
  • Rudy Goh,
  • Eamon P. Raith,
  • Krishnaswamy Sundararajan,
  • Timothy Kleinig

DOI
https://doi.org/10.1159/000536594

Abstract

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Introduction: Aspergillus flavus is a common cause of aspergillosis. Case presentation: A previously fit and well, immunocompetent 27-year old male living in Australia developed disseminated Aspergillus flavus complex infection with mediastinal and cardiac invasion, superior vena cava obstruction and stroke, with fatal haemorrhagic transformation. Conclusion: Aspergillus Flavus is a rare but important cause of serious disease in the immunocompetent.