Role of chondroitin sulfate in the regulation of neuroimmunoendocrine network interactions in patients with neurological symptoms in the post-covid period

Abstract

The review discusses the prospects for the use of chondroitin sulfate and its derivatives for new indications in patients with and myalgic encephalomyelitis/chronic fatigue syndrome after SARS-CoV-2 infection. The epidemiology, clinical manifestations, main mechanisms of the development of the dysregulation of neuroimmunoendocrine network interactions in long-term COVID-19 are considered. Modern data on the relationship between mechanisms of neuroprotective effects of chondroitin sulfate and its derivatives and their chemical structure characteristics have been analyzed. The position is argued according to which chondroitin sulfate and its derivatives can become promising drugs in prevention of the development of neuroimmunoendocrine network interactions disorders in COVID-19.

Keywords

• covid-19
• neurological symptoms
• neuroimmunoendocrine dysregulation
• chondroitin sulfate