Остеопороз и остеопатии (Apr 2007)

EFFEKTIVNOST' PRIMENENIYaKOMBINIROVANNOY TERAPII KAL'TsIEMS VYSOKIMI I SREDNIMI DOZAMI VITAMINA D3dlya profilaktiki postmenopauzal'nogo osteoporoza

  • A V DREVAL',
  • L A MARChENKOVA,
  • I V KRYuKOVA,
  • R S TIShENINA,
  • N V BALAShOVA,
  • L M PORTNOY,
  • N M MYLOV,
  • M P RUBIN

DOI
https://doi.org/10.14341/osteo2007120-24
Journal volume & issue
Vol. 10, no. 1
pp. 20 – 24

Abstract

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The aim of this study was to assess the effectiveness of the combined treatment with calcium and middle (400 mg daily) or high doses (800 mg daily) of vitamin D for prevention of osteoporosis in postmenopausal women with osteopenia in spine. Thirty patients, 45-70 years old, were divided into 3 equal groups: the women in the group 1 were treated with vitamin D3 400 IU. and calcium 1000 mg daily; the women in the group 2 received vitamin D3 800 IU and calcium 1000 mg daily; the patients from the group 3 did not receive any supplementation - the control 1 group. A significant increase in BMD was found at lumbar spine (+1.9 % after 6 months, p