Nature Communications (Jan 2020)

H2S-activatable near-infrared afterglow luminescent probes for sensitive molecular imaging in vivo

  • Luyan Wu,
  • Yusuke Ishigaki,
  • Yuxuan Hu,
  • Keisuke Sugimoto,
  • Wenhui Zeng,
  • Takashi Harimoto,
  • Yidan Sun,
  • Jian He,
  • Takanori Suzuki,
  • Xiqun Jiang,
  • Hong-Yuan Chen,
  • Deju Ye

DOI
https://doi.org/10.1038/s41467-020-14307-y
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 14

Abstract

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Afterglow imaging probes are of interest for in vivo imaging due to high signal-to-background ratios. Here, the authors report on an afterglow nanoparticle which is activated by hydrogen sulphide and demonstrate the measurement of hydrogen sulphide levels and the labelling of hepatic cancer specimens in vivo.