Nature Communications (Jul 2017)

Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells

  • Michel Enamorado,
  • Salvador Iborra,
  • Elena Priego,
  • Francisco J. Cueto,
  • Juan A. Quintana,
  • Sarai Martínez-Cano,
  • Ernesto Mejías-Pérez,
  • Mariano Esteban,
  • Ignacio Melero,
  • Andrés Hidalgo,
  • David Sancho

DOI
https://doi.org/10.1038/ncomms16073
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 11

Abstract

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Circulating memory cells include central memory T cells retaining the ability to enter the lymph nodes whereas tissue resident memory cells are confined to the parenchymal tissues. Here the authors explore the interplay between the two T-cell types and show that both cooperate in anti-tumour immunity.