Frontiers in Neuroscience (Sep 2019)
Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex
Abstract
Electrical stimulation of the primary somatosensory cortex using intracranial electrodes is crucial for the evocation of artificial somatosensations, typically tactile sensations associated with specific regions of the body, in brain-machine interface (BMI) applications. The qualitative characteristics of these artificially evoked somatosensations has been well documented. As of yet, however, the quantitative aspects of these evoked somatosensations, that is to say the quantitative relationship between intensity of electrical stimulation and perceived intensity of the resultant somatosensation remains obscure. This study aimed to explore this quantitative relationship by surface electrical stimulation of the primary somatosensory cortex in two human participants undergoing electrocorticographic monitoring prior to surgical treatment of intractable epilepsy. Electrocorticogram electrodes on the primary somatosensory cortical surface were stimulated with varying current intensities, and a visual analogue scale was employed to provide a quantitative measure of intensity of the evoked sensations. Evoked sensations included those of the thumb, tongue, and hand. A clear linear relationship between current intensity and perceived intensity of sensation was observed. These findings provide novel insight into the quantitative nature of primary somatosensory cortex electrical stimulation-evoked sensation for development of somatosensory neuroprosthetics for clinical use.
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