Cyclic Peptides KS-133 and KS-487 Multifunctionalized Nanoparticles Enable Efficient Brain Targeting for Treating Schizophrenia

• Kotaro Sakamoto,
• Seigo Iwata,
• Zihao Jin,
• Lu Chen,
• Tatsunori Miyaoka,
• Mei Yamada,
• Kaiga Katahira,
• Rei Yokoyama,
• Ami Ono,
• Satoshi Asano,
• Kotaro Tanimoto,
• Rika Ishimura,
• Shinsaku Nakagawa,
• Takatsugu Hirokawa,
• Yukio Ago,
• Eijiro Miyako

Affiliations

Kotaro Sakamoto

Research & Development Department, Ichimaru Pharcos Company Limited, Motosu, Gifu, Japan

Seigo Iwata

Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa, Japan

Zihao Jin

Laboratory of Biopharmaceutics, Osaka University, Suita, Osaka, Japan

Lu Chen

Laboratory of Biopharmaceutics, Osaka University, Suita, Osaka, Japan

Tatsunori Miyaoka

Laboratory of Biopharmaceutics, Osaka University, Suita, Osaka, Japan

Mei Yamada

Laboratory of Biopharmaceutics, Osaka University, Suita, Osaka, Japan

Kaiga Katahira

Laboratory of Biopharmaceutics, Osaka University, Suita, Osaka, Japan

Rei Yokoyama

Department of Cellular and Molecular Pharmacology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Hiroshima, Japan

Ami Ono

Department of Cellular and Molecular Pharmacology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Hiroshima, Japan

Satoshi Asano

Department of Cellular and Molecular Pharmacology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Hiroshima, Japan

Kotaro Tanimoto

Department of Orthodontics and Craniofacial Developmental Biology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Hiroshima, Japan

Rika Ishimura

Center for Supporting Drug Discovery and Life Science Research, Graduate School of Pharmaceutical Science, Osaka University, Suita, Osaka, Japan

Shinsaku Nakagawa

Laboratory of Biopharmaceutics, Osaka University, Suita, Osaka, Japan

Takatsugu Hirokawa

Division of Biomedical Science, Institute of Medicine, University of Tsukuba, Tsukuba, Japan

Yukio Ago

Laboratory of Biopharmaceutics, Osaka University, Suita, Osaka, Japan

Eijiro Miyako

Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa, Japan