Communications Biology (Apr 2023)

WSSV exploits AMPK to activate mTORC2 signaling for proliferation by enhancing aerobic glycolysis

  • Peng Zhang,
  • Hai-Jing Fu,
  • Li-Xia Lv,
  • Chen-Fei Liu,
  • Chang Han,
  • Xiao-Fan Zhao,
  • Jin-Xing Wang

DOI
https://doi.org/10.1038/s42003-023-04735-z
Journal volume & issue
Vol. 6, no. 1
pp. 1 – 18

Abstract

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AMPK and its downstream signaling pathways are implicated in the white spot syndrome virus (WSSV) response of the shrimp Marsupenaeus japonicus, with WSSV using this pathway to promote its proliferation.