A high-resolution map of non-crossover events reveals impacts of genetic diversity on mammalian meiotic recombination

Ran Li; Emmanuelle Bitoun; Nicolas Altemose; Robert W. Davies; Benjamin Davies; Simon R. Myers

doi:10.1038/s41467-019-11675-y

Nature Communications (Aug 2019)

A high-resolution map of non-crossover events reveals impacts of genetic diversity on mammalian meiotic recombination

Ran Li,
Emmanuelle Bitoun,
Nicolas Altemose,
Robert W. Davies,
Benjamin Davies,
Simon R. Myers

Affiliations

Ran Li: The Wellcome Centre for Human Genetics, Roosevelt Drive, University of Oxford
Emmanuelle Bitoun: The Wellcome Centre for Human Genetics, Roosevelt Drive, University of Oxford
Nicolas Altemose: The Wellcome Centre for Human Genetics, Roosevelt Drive, University of Oxford
Robert W. Davies: The Wellcome Centre for Human Genetics, Roosevelt Drive, University of Oxford
Benjamin Davies: The Wellcome Centre for Human Genetics, Roosevelt Drive, University of Oxford
Simon R. Myers: The Wellcome Centre for Human Genetics, Roosevelt Drive, University of Oxford

DOI: https://doi.org/10.1038/s41467-019-11675-y
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 15

Abstract

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During meiotic recombination, genetic information is transferred or exchanged between parental chromosome copies. Using a large hybrid mouse pedigree, the authors generated high-resolution maps of these transfer/exchange events and discovered new properties governing their processing and resolution.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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