Antiretrovirus drugs impair kidneys in HIV-infection

Abstract

Renal damage in HIV infection may result from direct action of HIV and from other causes including nephrotoxic action of medicines. HIV-infected patients receive a wide spectrum of medicines and can be placed in a risk group of drug-induced damage to the kidneys. Risk of nephrotoxicity should be considered in administration of antiretrovirus drugs in HIV patients. Strategy of preventive measures in relation to pharmacological harm to the kidneys consists in early detection of patients with high risk and correction of modifiable risk factors.

Keywords

• review
• hiv-infection
• antiretroviral drugs
• nephrotoxicity
• risk factors
• renal damage
• preventive measures