Evaluating the Effect of Staple Line Reinforcement on Reducing the Complications of Laparoscopic Sleeve Gastrectomy: A Randomized Clinical Trial

Abstract

Laparoscopic sleeve gastrectomy (LSG) is the most common bariatric surgery technique. In this technique, bleeding and staple line the leakage is considered as the most important complications. The current study aimed at evaluating the effect of reinforced the taple line on the level of bleeding and leakage after the surgery. Overall, 199 patients meeting the eligible criteria with morbid obesity (BMI>40 kg/m2) were enrolled in the study after signing the written informed consent. Patients were randomly allocated to intervention group (with reinforced staple line) and control group (Standard treatment) using simple randomization technique. Out of 199 cases, 120 (60%) were female, and 80 (40%) male; their mean BMI was 44.79± kg/m2, ranging from 40 to 58 kg/m2. Staple site bleeding was observed; therefore, no significant relationship was observed between the groups regarding bleeding decrease. Staple line leakage was observed in 2 cases of the control (without reinforcement) group and none of the cases in the intervention (with reinforcement) group. According to the results of the current study, no statistically significant relationship was observed between the groups regarding the level of leakage (P=0.249). Also, there was no significant relationship between age, gender, and BMI of cases, and the level of bleeding and leakage from the staple site. The average duration of surgery was 52.03 and 69.64 minutes for the control and intervention groups, respectively, which indicated prolonged surgery in the intervention group (P<0.001). The current study results indicated no significant relationship between the groups regarding the level of bleeding and leakage from the staple site.

Keywords

• Bariatric surgery
• Sleeve gastrectomy
• Staple line
• Leakage
• Bleedin