Vasoregulating endothelial function in essential arterial hypertension and chronic heart failure

Abstract

Mechanisms of vascular tonus regulation in patients with essential arterial hypertension (EAR) and chronic heart failure (CHF) were examined by high-definition ultrasound method. EAH patients demonstrated substantially disturbed endothelium-dependent mechanisms of vascular tonus regulation, with intact endothelium-independent mechanisms. In CHE individuals, both endothelium-dependent and independent vascular reactions were disturbed. The observed changes in vasomotor reactions might precede morphological changes in vascular wall.

Keywords

• arterial hypertension
• chronic heart failure
• vascular tonus regulation
• endothelial function