Clinical, Cosmetic and Investigational Dermatology (May 2023)
Efficacy of Oxybrasion and Cosmetic Acids on Selected Skin Parameters in the Treatment with Acne Vulgaris
Abstract
Karolina Chilicka,1 Monika Rusztowicz,1 Aleksandra M Rogowska,2 Renata Szyguła,1 Danuta Nowicka3 1Department of Health Sciences, Institute of Health Sciences, University of Opole, Opole, Poland; 2Department of Social Sciences, Institute of Psychology, University of Opole, Opole, Poland; 3Department of Dermatology, Venereology and Allergology, Wrocław Medical University, Wrocław, PolandCorrespondence: Karolina Chilicka, Department of Health Sciences, Institute of Health Sciences, University of Opole, Katowicka 68 Street, Opole, 45-040, Poland, Tel +48665439443, Email [email protected]: The present study aimed to evaluate the efficacy of an oxybrasion treatment applied alone and an oxybrasion treatment combined with cosmetic acids in improving acne-prone skin and selected skin parameters.Patients and Methods: A single-blind placebo study in a sample of 44 women diagnosed with acne vulgaris was conducted. Group A (n = 22) had a series of five oxybrasion treatments, while group B (n = 22) received a synergy of five oxybrasion treatments and a mixture of phytic, pyruvic, and lactic and lactic ferulic acids at 40% pH 1.4. Cosmetic treatments were performed every 14 days, and The Derma Unit SCC3 apparatus (Courage & Khazaka, Cologne, Germany) Sebumeter SM 815 and Corneometer CM825 and GAGS scale were used to check their effectiveness.Results: A Bonferroni post hoc test showed that group A and B did not differ from each other in acne severity before treatment (p = 1.00). However, these samples differed significantly after treatment (p < 0.001), suggesting that combined treatment of oxybrasion and cosmetic acids has a better effect than oxybrasion alone. Also, two treatment conditions (before and after) were statistically different for groups A and B separately (p < 0.001), indicating a similar efficacy of both treatments on acne severity.Conclusion: Cosmetic treatments improved acne-prone skin and selected skin parameters. Better results were obtained by combining an oxybrasion treatment with cosmetic acids.Clinical Trial Approval: The clinical trial with ID ISRCTN 28257448 approved this study.Keywords: acne vulgaris, oxybrasion, cosmetic acids, sebumeter, corneometer
