Balkan Journal of Medical Genetics (Mar 2024)

Association Between the Polymorphism of Angiotensin-Converting Enzyme Gene and Interleukin-1 Beta Gene and the Response to Erythropoietin Therapy in Dialysis Patients with Anemia

  • Dzekova-Vidimliski P,
  • Eftimovska-Otovikj N,
  • Nikolov I G,
  • Selim Gj,
  • Rambabova-Bushljetik I,
  • Pushevski V,
  • Karanfilovski V,
  • Matevska-Geshovska N,
  • Dimovski A

DOI
https://doi.org/10.2478/bjmg-2023-0022
Journal volume & issue
Vol. 26, no. 2
pp. 27 – 34

Abstract

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The polymorphism of the angiotensin-converting enzyme (ACE) gene and interleukin-1 beta (IL-1b) gene could be associated with resistance in the treatment of anemia in dialysis patients with recombinant human erythropoietin (rHuEPO). The aim of the study was to evaluate the association between the polymorphism of the ACE and IL-1b genes and the response to rHuEPO therapy in dialysis patients with anemia.

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