Communications Biology (Nov 2021)

Location-dependent threat and associated neural abnormalities in clinical anxiety

  • Benjamin Suarez-Jimenez,
  • Nicholas L. Balderston,
  • James A. Bisby,
  • Joseph Leshin,
  • Abigail Hsiung,
  • John A. King,
  • Daniel S. Pine,
  • Neil Burgess,
  • Christian Grillon,
  • Monique Ernst

DOI
https://doi.org/10.1038/s42003-021-02775-x
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 12

Abstract

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Suarez-Jimenez and colleagues use a shock and safe zone experiment with fMRI imaging to examine how pathological anxiety disorders are manifested in the brain. Their findings suggest that safe and dangerous zones within the experiment alter activation in different brain regions.