The imaging features of perivascular spaces in differentiation of cerebral small vessel disease and multiple sclerosis

Abstract

Objective To investigate the imaging features differences of perivascular spaces(PVS) between cerebral small vessel disease(cSVD) and multiple sclerosis(MS). Methods The clinical data of 27 patients diagnosed with cSVD and 32 patients diagnosed with MS were collected retrospectively from January 2015 to December 2017. The grade of PVS in the centrum semiovale and basal ganglia were recorded and the sum of scores in the two regions were calculated in both diseases. Results The score of PVS in the area of basal ganglia and the total score in cSVD group were 1 (1,2) and 3 (2,4),which were both higher than 1 (1,1) and 1 (1,2) score in MS group respectively(Z=7.960, P=0.012; Z=14.033, P= 0.001). The score of PVS in centrum semiovale were similar in cSVD group and MS group[1(1,2)score vs. 0 (0, 1) score; Z =4.872, P =0.057]. Conclusions In the areas of basal ganglia, PVS are more common in cSVD patients than MS patients.

Keywords

• Cerebra lsmall vessel diseases; Multiple sclerosis; Perivascular spaces(notin MeSH)