PD-1 blockade after bispecific LV20.19 CAR T modulates CAR T-cell immunophenotype without meaningful clinical response

• Joanna Zurko,
• Katherine Chaney,
• John M. Astle,
• Bryon D. Johnson,
• Parameswaran Hari,
• Nirav N. Shah

Affiliations

Joanna Zurko

BMT and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI

Katherine Chaney

BMT and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI

John M. Astle

Department of Pathology, Medical College of Wisconsin, Milwaukee, WI

Bryon D. Johnson

BMT and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI

Parameswaran Hari

BMT and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI

Nirav N. Shah

BMT and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI