Data retrieved from in silico evaluation of vaccine potential of ZnuD protein in Acinetobacter baumannii

Abstract

The nosocomial Acinetobacter baumannii is one of the most opportunistic pathogens that resists almost a broad range of antibiotics. Some bacterial metal acquisition systems are introduced as potential virulence factors in pathogen-host interaction. Bacterial zinc uptake (Znu) systems are critical transporters that play a major role in the survival of the pathogen and the establishment of infections. In silico characterization of ZnuD shows that it is an outer membrane protein with high conservancy rates in most Acinetobacter baumannii strains. The in silico derived physicochemical properties, structural and conserved immunoinformatic prediction data among Acinetobacter baumannii strains confirm that ZnuD belongs to Ton B dependent siderophore receptor families and is considered as a potential vaccine candidate. A more detailed interpretation of the data presented in this article is provided in “Identification and immunogenic properties of recombinant ZnuD protein loops of Acinetobacter baumannii” [1].

Keywords

• Acinetobacter baumannii.
• ZnuD
• Physicochemical properties.
• Secondary structure