Current insights and future directions of LncRNA Morrbid in disease pathogenesis

Haiqiong Yang; Jiali Gao; Zaiyong Zheng; Yang Yu; Chunxiang Zhang

Heliyon (Sep 2024)

Current insights and future directions of LncRNA Morrbid in disease pathogenesis

Haiqiong Yang,
Jiali Gao,
Zaiyong Zheng,
Yang Yu,
Chunxiang Zhang

Affiliations

Haiqiong Yang: Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, China; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, (Collaborative Innovation Center for Prevention of Cardiovascular Diseases), Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China
Jiali Gao: School of Pharmacy, Southwest Medical University, Luzhou, China; Department of pharmacy, Luzhou people's hospital, Luzhou, China
Zaiyong Zheng: Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, China; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, (Collaborative Innovation Center for Prevention of Cardiovascular Diseases), Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China
Yang Yu: Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, China; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, (Collaborative Innovation Center for Prevention of Cardiovascular Diseases), Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China
Chunxiang Zhang: Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, China; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, (Collaborative Innovation Center for Prevention of Cardiovascular Diseases), Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China; Corresponding author. Southwest Medical University, No.1 Section 1, Xiang Lin Road, Luzhou, 646000, China.

Journal volume & issue: Vol. 10, no. 17
p. e36681

Abstract

Read online

Non-coding RNAs have emerged as important regulators of gene expression and contributors to many diseases. LncRNA Morrbid, a long non-coding RNA, has been widely studied in recent years. Current literature reports that lncRNA Morrbid is involved in various diseases such as tumors, cardiovascular diseases, inflammatory diseases and metabolic disorder. However, controversial conclusions exist in current studies. As a potential therapeutic target, it is necessary to comprehensively review the current evidence. In this work, we carefully review the literature on Morrbid and discuss each of the hot topics related to lncRNA Morrbid.

Published in Heliyon

ISSN: 2405-8440 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Science: Science (General); Social Sciences: Social sciences (General)
Website: https://www.cell.com/heliyon/home

About the journal

Abstract

Keywords