High-Surety Isothermal Amplification and Detection of SARS-CoV-2

Sanchita Bhadra; Timothy E. Riedel; Simren Lakhotia; Nicholas D. Tran; Andrew D. Ellington

doi:10.1128/mSphere.00911-20

mSphere (Jun 2021)

High-Surety Isothermal Amplification and Detection of SARS-CoV-2

Sanchita Bhadra,
Timothy E. Riedel,
Simren Lakhotia,
Nicholas D. Tran,
Andrew D. Ellington

Affiliations

Sanchita Bhadra: ORCiD; Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, Texas, USA
Timothy E. Riedel: Freshman Research Initiative, DIY Diagnostics Stream, The University of Texas at Austin, Austin, Texas, USA
Simren Lakhotia: Freshman Research Initiative, DIY Diagnostics Stream, The University of Texas at Austin, Austin, Texas, USA
Nicholas D. Tran: Freshman Research Initiative, DIY Diagnostics Stream, The University of Texas at Austin, Austin, Texas, USA
Andrew D. Ellington: ORCiD; Department of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, Texas, USA

DOI: https://doi.org/10.1128/mSphere.00911-20
Journal volume & issue: Vol. 6, no. 3

Abstract

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One of the key approaches to treatment and control of infectious diseases, such as COVID-19, is accurate and rapid diagnostics that is widely deployable in a timely and scalable manner. To achieve this, it is essential to go beyond the traditional gold standard of quantitative PCR (qPCR) that is often faced with difficulties in scaling due to the complexity of infrastructure and human resource requirements.

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

About the journal