Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping

Marie N. Bongiovanni; Julien Godet; Mathew H. Horrocks; Laura Tosatto; Alexander R. Carr; David C. Wirthensohn; Rohan T. Ranasinghe; Ji-Eun Lee; Aleks Ponjavic; Joelle V. Fritz; Christopher M. Dobson; David Klenerman; Steven F. Lee

doi:10.1038/ncomms13544

Nature Communications (Dec 2016)

Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping

Marie N. Bongiovanni,
Julien Godet,
Mathew H. Horrocks,
Laura Tosatto,
Alexander R. Carr,
David C. Wirthensohn,
Rohan T. Ranasinghe,
Ji-Eun Lee,
Aleks Ponjavic,
Joelle V. Fritz,
Christopher M. Dobson,
David Klenerman,
Steven F. Lee

Affiliations

Marie N. Bongiovanni: Department of Chemistry, University of Cambridge
Julien Godet: Laboratoire de Biophotonique et Pharmacologie, UMR CNRS 7213, Université de Strasbourg
Mathew H. Horrocks: Department of Chemistry, University of Cambridge
Laura Tosatto: Department of Chemistry, University of Cambridge
Alexander R. Carr: Department of Chemistry, University of Cambridge
David C. Wirthensohn: Department of Chemistry, University of Cambridge
Rohan T. Ranasinghe: Department of Chemistry, University of Cambridge
Ji-Eun Lee: Department of Chemistry, University of Cambridge
Aleks Ponjavic: Department of Chemistry, University of Cambridge
Joelle V. Fritz: Luxembourg Centre for Systems Biomedicine, University of Luxembourg
Christopher M. Dobson: Department of Chemistry, University of Cambridge
David Klenerman: Department of Chemistry, University of Cambridge
Steven F. Lee: Department of Chemistry, University of Cambridge

DOI: https://doi.org/10.1038/ncomms13544
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 9

Abstract

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Many super-resolution imaging techniques use fluorescence emission intensity to obtain precise positional information, but other spectral information is ignored. Here, the authors develop a method that records the spectrum and position of single dye molecules to map the hydrophobicity of a surface.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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