NEW OPPORTUNITIES OF TREATMENT OF DIFFERENT TYPES OF JUVENILE ARTHRITIS WITH MONOCLONAL ANTIBODIES TO THE INTERLEUKIN 6 RECEPTOR

E.I. Alexeeva; R.V. Denisova; S.I. Valieva; T.M. Bzarova; A.O. Lisitsyn

Вопросы современной педиатрии (Jan 2010)

NEW OPPORTUNITIES OF TREATMENT OF DIFFERENT TYPES OF JUVENILE ARTHRITIS WITH MONOCLONAL ANTIBODIES TO THE INTERLEUKIN 6 RECEPTOR

E.I. Alexeeva,
R.V. Denisova,
S.I. Valieva,
T.M. Bzarova,
A.O. Lisitsyn

Affiliations

E.I. Alexeeva: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
R.V. Denisova: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
S.I. Valieva: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
T.M. Bzarova: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
A.O. Lisitsyn: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow

Journal volume & issue: Vol. 9, no. 1
pp. 52 – 61

Abstract

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The article observes the data on the role of interleukin (IL) 6 in pathogenesis of rheumatoid arthritis and treatment of rheumatoid arthritis and different types of juvenile arthritis with blocker IL 6 receptor (tocilizumab). The data on multicenter open-labeled and double-blinded randomized studies on effectiveness and safety of tocilizumab are reviewed. The results of studies showed high effectiveness and safety of tocilizumab in treatment of rheumatoid arthritis and juvenile arthritis. Key words: children, rheumatoid arthritis, juvenile arthritis, interleukin 6, treatment, tocilizumab.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(1):52-61)

Published in Вопросы современной педиатрии

ISSN: 1682-5527 (Print); 1682-5535 (Online)
Publisher: "Paediatrician" Publishers LLC
Country of publisher: Russian Federation
LCC subjects: Medicine: Pediatrics
Website: https://vsp.spr-journal.ru

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