Nature Communications (Oct 2020)

Protease circuits for processing biological information

  • Brandon Alexander Holt,
  • Gabriel A. Kwong

DOI
https://doi.org/10.1038/s41467-020-18840-8
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

Read online

In contrast to genetic circuits, here the authors develop protein biocircuits based on proteases. They show these activity-based circuits can execute Boolean logic for programmable drug delivery and perform fuzzy logic to solve a mathematical oracle problem, Learning Parity with Noise.