A Case Report of Al-Amyloidosis with «Hepatic Disguise» of Nephrotic Syndrome

Abstract

Amyloidosis is characterized by damage to several organ systems, which leads to diagnostic delays and progression of the pathological process. The described clinical case demonstrates a long diagnostic search in a patient with AL-amyloidosis. According to the literature, the most often described manifestation of the disease is kidney damage that manifests as nephrotic syndrome. This case is interesting because the reason for hospitalization was liver damage. Laboratory tests revealed cholestatic and cytolytic syndromes and dyslipidemia. Differential diagnostic included diseases with liver damage. In the hospital nephrotic syndrome was identifi ed, renal biopsy was performed that proved the diagnosis of AL-amyloidosis with combined damage to the gastrointestinal tract, liver and kidneys.

Keywords

• al-amyloidosis
• nephrotic syndrome
• renal biopsy