Thrombosis Journal (Mar 2021)
Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore
- Chuen Wen Tan,
- Bingwen Eugene Fan,
- Winnie Z. Y. Teo,
- Moon Ley Tung,
- Humaira Shafi,
- Dheepa Christopher,
- Shuwei Zheng,
- Wee Ming Peh,
- Stephrene Seok Wei Chan,
- Vanessa Cui Lian Chong,
- Christian Aledia Gallardo,
- Cheng Chieh Ray Chang,
- Li Min Ling,
- Jing Yuan Tan,
- Ken Cheah Hooi Lee,
- Ghee Chee Phua,
- Benjamin Pei Zhi Cherng,
- Jenny Guek Hong Low,
- Vui Kian Ho,
- Vishnu Prasad,
- Lester Jung Long Wong,
- Cheryl Xiu Qi Lim,
- Yen Lin Chee,
- Kiat Hoe Ong,
- Lai Heng Lee,
- Heng Joo Ng,
- Eng Soo Yap,
- on behalf of the Thrombosis Haemostasis Workgroup of Singapore Society of Haematology
Affiliations
- Chuen Wen Tan
- Department of Haematology, Singapore General Hospital
- Bingwen Eugene Fan
- Department of Haematology, Tan Tock Seng Hospital
- Winnie Z. Y. Teo
- Department of Haematology-oncology, National University Cancer Institute
- Moon Ley Tung
- Department of Haematology-oncology, National University Cancer Institute
- Humaira Shafi
- Department of Infectious Diseases, Changi General Hospital
- Dheepa Christopher
- Department of Haematology, Tan Tock Seng Hospital
- Shuwei Zheng
- Department of General Medicine, Sengkang General Hospital
- Wee Ming Peh
- Department of General Medicine, Sengkang General Hospital
- Stephrene Seok Wei Chan
- Department of Haematology, Tan Tock Seng Hospital
- Vanessa Cui Lian Chong
- Department of Haematology, Tan Tock Seng Hospital
- Christian Aledia Gallardo
- Department of Haematology, Tan Tock Seng Hospital
- Cheng Chieh Ray Chang
- Department of Haematology, Tan Tock Seng Hospital
- Li Min Ling
- Department of Infectious Diseases, National Centre for Infectious Disease
- Jing Yuan Tan
- Department of Respiratory and Critical Care Medicine, Singapore General Hospital
- Ken Cheah Hooi Lee
- Department of Respiratory and Critical Care Medicine, Singapore General Hospital
- Ghee Chee Phua
- Department of Respiratory and Critical Care Medicine, Singapore General Hospital
- Benjamin Pei Zhi Cherng
- Department of Infectious Diseases, Singapore General Hospital
- Jenny Guek Hong Low
- Department of Infectious Diseases, Singapore General Hospital
- Vui Kian Ho
- Department of Intensive Care Medicine, Sengkang General Hospital
- Vishnu Prasad
- Department of Laboratory Medicine, Khoo Teck Puat Hospital
- Lester Jung Long Wong
- Division of Medicine, Khoo Teck Puat Hospital
- Cheryl Xiu Qi Lim
- Department of Haematology-oncology, National University Cancer Institute
- Yen Lin Chee
- Department of Haematology-oncology, National University Cancer Institute
- Kiat Hoe Ong
- Department of Haematology, Tan Tock Seng Hospital
- Lai Heng Lee
- Department of Haematology, Singapore General Hospital
- Heng Joo Ng
- Department of Haematology, Singapore General Hospital
- Eng Soo Yap
- Department of Haematology-oncology, National University Cancer Institute
- on behalf of the Thrombosis Haemostasis Workgroup of Singapore Society of Haematology
- DOI
- https://doi.org/10.1186/s12959-021-00268-9
- Journal volume & issue
-
Vol. 19,
no. 1
pp. 1 – 7
Abstract
Abstract Background Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients. Method and results This is a national multicenter retrospective observational study involving all consecutive adult COVID-19 patients who required intensive care units (ICU) admission between 23 January 2020 and 30 April 2020 in Singapore. One hundred eleven patients were included and the venous and arterial thrombotic rates in ICU were 1.8% (n = 2) and 9.9% (n = 11), respectively. Major bleeding rate was 14.8% (n = 16). Conclusions Critically ill COVID-19 patients in Singapore have lower venous thromboembolism but higher arterial thrombosis rates and bleeding manifestations than other reported cohorts.
Keywords
