Acta Biomedica Scientifica (Apr 2015)
Microbial landscape of operated patients with limited sterile pancreatic necrosis in different periods of complex treatment
Abstract
The method of gas chromatography - mass spectrometry was studied for the first time in patients with sterile pancreatic necrosis. The parameters defined in the normal conditions are presented. We studied the microbial landscape of patients with sterile pancreatic necrosis in the dynamics of complex treatment. Qualitative analysis was based on the comparison of retention times and mass specter of the total corresponding pure compounds using a library of standard data and mixtures N1ST08.L. We detected elevated markers in patients with acute pancreatitis associated with anaerobic microflora (peptostreptococcus, staphylococci, eubacteria, fusobacterium, clostridium), and at the same time low level of lactobacilli, bifidobacteria, some ruminococcus, actinomycetes and other microorganisms that caused dysbiosis.