Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment

Senk Barbara; Goricar Katja; Kovac Viljem; Dolzan Vita; Franko Alenka

doi:10.2478/raon-2019-0009

Radiology and Oncology (Mar 2019)

Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment

Senk Barbara,
Goricar Katja,
Kovac Viljem,
Dolzan Vita,
Franko Alenka

Affiliations

Senk Barbara: Pharmacogenetics Laboratory, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
Goricar Katja: Pharmacogenetics Laboratory, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
Kovac Viljem: Institute of Oncology Ljubljana, Ljubljana, Slovenia
Dolzan Vita: Pharmacogenetics Laboratory, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
Franko Alenka: Clinical Institute of Occupational Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia

DOI: https://doi.org/10.2478/raon-2019-0009
Journal volume & issue: Vol. 53, no. 1
pp. 96 – 104

Abstract

Read online

Malignant mesothelioma (MM) is an asbestos related aggressive tumor with poor prognosis. The aim of this study was to investigate if aquaporin 1 (AQP1) genetic polymorphisms influence the risk of MM and the response to cisplatin based MM treatment.

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

About the journal

Abstract

Keywords