Induction chemotherapy, chemoradiotherapy and consolidation chemotherapy in preoperative treatment of rectal cancer - long-term results of phase II OIGIT-01 Trial

Golo Danijela; But-Hadzic Jasna; Anderluh Franc; Brecelj Erik; Edhemovic Ibrahim; Jeromen Ana; Omejc Mirko; Oblak Irena; Secerov-Ermenc Ajra; Velenik Vaneja

doi:10.2478/raon-2018-0028

Radiology and Oncology (Sep 2018)

Induction chemotherapy, chemoradiotherapy and consolidation chemotherapy in preoperative treatment of rectal cancer - long-term results of phase II OIGIT-01 Trial

Golo Danijela,
But-Hadzic Jasna,
Anderluh Franc,
Brecelj Erik,
Edhemovic Ibrahim,
Jeromen Ana,
Omejc Mirko,
Oblak Irena,
Secerov-Ermenc Ajra,
Velenik Vaneja

Affiliations

Golo Danijela: Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia
But-Hadzic Jasna: Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Anderluh Franc: Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Brecelj Erik: Department of Surgery, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Edhemovic Ibrahim: Department of Surgery, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Jeromen Ana: Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Omejc Mirko: Department of Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia
Oblak Irena: Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Secerov-Ermenc Ajra: Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Velenik Vaneja: Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia

DOI: https://doi.org/10.2478/raon-2018-0028
Journal volume & issue: Vol. 52, no. 3
pp. 267 – 274

Abstract

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The purpose of the study was to improve treatment efficacy for locally advanced rectal cancer (LARC) by shifting half of adjuvant chemotherapy preoperatively to one induction and two consolidation cycles.

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

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Abstract

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