Citrate, pyruvate, and lactate contaminants of commercial serum albumin

Abstract

Commercial serum albumin was found to contain lactate, pyruvate, and especially citrate in addition to fatty acids. Glucose, aspartate, and α-ketoglutarate were also present but at lower concentrations. Charcoal treatment followed by prolonged dialysis was effective in removing most of these contaminants.

Keywords

• contaminants
• citrate
• pyruvate
• lactate
• free fatty acids
• charcoal