eJHaem (Feb 2024)

Aleukemic congenital leukemia cutis preceding monocytic leukemia with favorable outcome: A case report

  • Caroline Lo Presti,
  • Gautier Szymanski,
  • Christine Lefebvre,
  • Marie‐Christine Jacob,
  • Pascal Mossuz,
  • Hugo Gil

DOI
https://doi.org/10.1002/jha2.861
Journal volume & issue
Vol. 5, no. 1
pp. 162 – 165

Abstract

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Abstract A newborn girl had typical “blueberry muffin” skin lesions, which shows histopathologic features of monocytic leukemia cutis. The systemic leukemia was demonstrated after one month of life. She was treated by chemotherapy, including induction and three consolidation cures, according to the ELAM02 protocol, which led to complete remission. This case report with congenital form of AML5 cutaneous localization, preceding systemic involvement, with a 5‐year follow‐up and positive outcome is remarkable.

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