Pulmonary alveolar microlithiasis diagnosed with radiography, CT, and bone scintigraphy

Emad Alkhankan, MD; Hasan Yamin, MD; Hazim Bukamur, MD; Fadi Alkhankan, MD; Yousef Shweihat, MD; Fuad Zeid, MD

Radiology Case Reports (Jun 2019)

Pulmonary alveolar microlithiasis diagnosed with radiography, CT, and bone scintigraphy

Emad Alkhankan, MD,
Hasan Yamin, MD,
Hazim Bukamur, MD,
Fadi Alkhankan, MD,
Yousef Shweihat, MD,
Fuad Zeid, MD

Affiliations

Emad Alkhankan, MD: Pulmonary and Critical Care, Marshall University, 1249 15th St, Huntington, WV 25701, USA; Corresponding author.
Hasan Yamin, MD: Pulmonary and Critical Care, Marshall University, 1249 15th St, Huntington, WV 25701, USA
Hazim Bukamur, MD: Pulmonary and Critical Care, Marshall University, 1249 15th St, Huntington, WV 25701, USA
Fadi Alkhankan, MD: Pulmonary and Critical Care, Marshall University, 1249 15th St, Huntington, WV 25701, USA; Pulmonary and Critical Care, Mclaren Oakland, Pontiac, MI, USA
Yousef Shweihat, MD: Pulmonary and Critical Care, Marshall University, 1249 15th St, Huntington, WV 25701, USA
Fuad Zeid, MD: Pulmonary and Critical Care, Marshall University, 1249 15th St, Huntington, WV 25701, USA

Journal volume & issue: Vol. 14, no. 6
pp. 775 – 777

Abstract

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Pulmonary alveolar microlithiasis is rare disease characterized by accumulation of calcium phosphate microlithis in the alveoli. The pathogenesis relates to mutation in the gene SLC34A2 (solute carrier family 34 member 2) located on chromosome 4p15.2, which produces a defective sodium-phosphate cotransporter in alveolar epithelial type-2 cells, making these cells unable to clear phosphorus released during recycling of surfactant [1]. Keywords: SLC34A2 gene, Alveolar microlithiasis, Interstitial lung disease, Bone scan scintography of the lung, Hypoxemia, Lung calcification

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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