Thermosensitive hydrogel for in situ-controlled methotrexate delivery

Carrillo-Castillo Teresa Darlen; Luna-Velasco Antonia; Zaragoza-Contreras Erasto Armando; Castro-Carmona Javier Servando

doi:10.1515/epoly-2021-0085

e-Polymers (Nov 2021)

Thermosensitive hydrogel for in situ-controlled methotrexate delivery

Carrillo-Castillo Teresa Darlen,
Luna-Velasco Antonia,
Zaragoza-Contreras Erasto Armando,
Castro-Carmona Javier Servando

Affiliations

Carrillo-Castillo Teresa Darlen: Department of Engineering and Materials Chemistry, Centro de Investigación en Materiales Avanzados, S.C. Miguel de Cervantes No. 120, Complejo Industrial Chihuahua, C.P. 31136, Chihuahua, Chih, Mexico
Luna-Velasco Antonia: Department of Environment and Energy, Centro de Investigación en Materiales Avanzados, S.C. Miguel de Cervantes No. 120, Complejo Industrial Chihuahua, C.P. 31136, Chihuahua, Chih, Mexico
Zaragoza-Contreras Erasto Armando: Department of Engineering and Materials Chemistry, Centro de Investigación en Materiales Avanzados, S.C. Miguel de Cervantes No. 120, Complejo Industrial Chihuahua, C.P. 31136, Chihuahua, Chih, Mexico
Castro-Carmona Javier Servando: Engineering in Design and Agricultural/Food Automation, Universidad Autónoma de Ciudad Juárez, Manuel Díaz H. No. 518-B Zona Pronaf Condominio, C.P. 32315, Ciudad Juárez, Chih, Mexico

DOI: https://doi.org/10.1515/epoly-2021-0085
Journal volume & issue: Vol. 21, no. 1
pp. 910 – 920

Abstract

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MTX is loaded and released in a controlled manner over 14 h, under physiological conditions, from an amphiphilic triblock copolymer with a sol–gel phase change at 36.5°C.

Published in e-Polymers

ISSN: 1618-7229 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Technology: Chemical technology: Polymers and polymer manufacture
Website: https://www.degruyter.com/view/j/epoly

About the journal

Abstract

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