International Journal of COPD (Mar 2021)
Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease
Abstract
Sander Talman,1 Sevim Uzun,2 Remco S Djamin,1 Sara J Baart,3 Marco JJH Grootenboers,1 Joachim Aerts,2 Menno van der Eerden2 1Amphia Hospital Breda, Department of Pulmonary Medicine, Breda, 4800RK, the Netherlands; 2Erasmus Medical Centre Rotterdam, Department of Pulmonary Medicine, Rotterdam, 3015 CE, the Netherlands; 3Erasmuc Medical Centre Rotterdam, Department of Biostatistics, Rotterdam, 3015 CE, the NetherlandsCorrespondence: Sander Talman Tel +31 76 595 5351Email [email protected]: Macrolides are effective in reducing the number of exacerbations in COPD patients with the frequent exacerbator phenotype. Our study did not show a persistent effect of azithromycin on exacerbation frequencies after more than one year of usage.Keywords: Macrolide, long-term, exacerbations, COPD, COLUMBUS