Predicting Gastric Cancer Molecular Subtypes from Gene Expression Data

Abstract

Stomach cancer is a complex disease and one of the leading causes of cancer mortality in the world. With the view to improve patient diagnosis and prognosis, it has been stratified into four molecular subtypes. In this work, we compare the results of multiple machine learning algorithms for the prediction of stomach cancer molecular subtypes from gene expression data. Moreover, we show the importance of decorrelating clinical and technical covariates.

Keywords

• gene expression
• gastric cancer
• disease classification
• machine learning