Revista Cubana de Hematología, Inmunología y Hemoterapia (Apr 2003)

Alteraciones de las inmunoglobulinas en pacientes con enfermedad de Hodgkin Alterations of immunoglobulins in patients with Hodgkin disease

  • Ada A Arce Hernández,
  • Rinaldo Villaescusa Blanco,
  • Julio C Merlín Linares,
  • Ana M Guerreiro Hernández,
  • Porfirio Hernández Ramírez

Journal volume & issue
Vol. 19, no. 1
p. 0

Abstract

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Se determinaron las concentraciones de IgG, IgA e IgM en el suero de 24 pacientes adultos con enfermedad de Hodgkin. Se detectó una disminución significativa (p The concentrations of IgG, IgA and IgM were determined in the serum of 24 adult patients with Hodgkin disease. It was detected a significant decrease (p<0.001) of the 3 immunoglobulins in the total group of patients on comparing them with the normal controls A reduction of the studied immunoglobulins was proved in patients at the most advanced clinical stages, IIIB and IVB. IgG and IgM maintained themselves within the normal limits at stage IIA. IgA did not do so, since it was already reduced. The data obtained in our paper suggest a possible association between the IgG and IgM levels and the spreading of the disease

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