Nicotinamide prevention in diabetes-induced alterations in the rat liver

Kuchmerovska Tamara; Yanitska Lesya; Horkunenko Oksana; Guzyk Mykhailo; Tykhonenko Tetiana; Pryvrotska Irina

doi:10.2478/enr-2023-0031

Endocrine Regulations (Jan 2023)

Nicotinamide prevention in diabetes-induced alterations in the rat liver

Kuchmerovska Tamara,
Yanitska Lesya,
Horkunenko Oksana,
Guzyk Mykhailo,
Tykhonenko Tetiana,
Pryvrotska Irina

Affiliations

Kuchmerovska Tamara: 1Department of Vitamin and Coenzyme Biochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine
Yanitska Lesya: 2Department of Medical Biochemistry and Molecular Biology, Bogomolets National Medical University, Kyiv, Ukraine
Horkunenko Oksana: 2Department of Medical Biochemistry and Molecular Biology, Bogomolets National Medical University, Kyiv, Ukraine
Guzyk Mykhailo: 1Department of Vitamin and Coenzyme Biochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine
Tykhonenko Tetiana: 1Department of Vitamin and Coenzyme Biochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine
Pryvrotska Irina: 3Gorbachevsky Ternopil’ State Medical University, Ministry of Public Health of Ukraine, Ternopil’, Ukraine

DOI: https://doi.org/10.2478/enr-2023-0031
Journal volume & issue: Vol. 57, no. 1
pp. 279 – 291

Abstract

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Objective. The study was performed to elucidate whether nicotinamide (NAm) can attenuate the diabetes-induced liver damage by correction of ammonia detoxifying function and disbalance of NAD-dependent processes in diabetic rats.

Published in Endocrine Regulations

ISSN: 1336-0329 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://sciendo.com/journal/ENR

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Abstract

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