Iranian Journal of Reproductive Medicine (Jan 2011)

Unexplained infertility as primary presentation of celiac disease, a case report and literature review

  • Mohammadreza Ghadir,
  • Abolfazl Iranikhah,
  • Mahboubeh Jandaghi,
  • Farahnaz Joukar,
  • Massih Sedigh-Rahimabadi,
  • Fariborz Mansour-Ghanaei

Journal volume & issue
Vol. 9, no. 2
pp. 135 – 140

Abstract

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Background: Celiac sprue (gluten sensitive enteropathy) is an autoimmune disease which is hereditary and its pathology mainly bases on immunologic intolerance to gluten. It has a vast variety of signs and symptoms and its clinical features range from a silent disease to a typical gastrointestinal disorder. In this study we reviewed and summarized some other related issues about this disease and its relation with infertility.Case: The case is a 26 years old lady who had referred to a gynecologist because of infertility for 2 years and later it revealed that she has celiac sprue.Conclusion: Screening for its silent or subtle types especially among suspicious cases such as unexplained infertility seems to be a cost effective action. Meanwhile, in time administration of a gluten-free diet can lead to an almost complete cure

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