Human Vaccines & Immunotherapeutics (Dec 2024)

A bibliometric analysis of oncolytic virotherapy combined with immunotherapy

  • Ting Zhang,
  • Shitao Jiang,
  • Lei Zhang,
  • Yaoge Liu,
  • Han Zheng,
  • Haitao Zhao,
  • Shunda Du,
  • Yiyao Xu,
  • Xin Lu

DOI
https://doi.org/10.1080/21645515.2024.2406621
Journal volume & issue
Vol. 20, no. 1

Abstract

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Oncolytic virotherapy in combination with immunotherapy has demonstrated significant survival benefits in some types of cancer. Here, we summarized the development, research hotpots and potential trends of the combination therapy using visual bibliometric analysis. A total of 712 articles were retrieved on June 21, 2023. The USA was the top contributors of any country (325, 45.65%), and the Rluk Research Libraries UK ranked first (43, 6.03%) of any institutions. The Journal for ImmunoTherapy of Cancer was with the largest publications (60, 8.43%). ‘Tumor microenvironment’ and ‘delivery’ were citation keywords with the strongest ongoing bursts. Research fronts in the future may focus on the methods of virus delivery and tumor microenvironment modulation. Futhermore, the most extensively studied cancer were melanoma, glioma and hepatocellular carcinoma.

Keywords